synthetic lethality

English

Noun

synthetic lethality (usually uncountable, plural synthetic lethalities)

1. (genetics) A type of genetic interaction in which two (or more) mutations which are not lethal when occurring singly in a cell are lethal when they occur together in the same cell.

References

• Maloy, Stanley with French-Mischo, Stephanie (2002 July 16) “Synthetic Lethal Mutations”, in Microbial Genetics‎^[1], San Diego State University, archived from the original on 13 May 2003
• Le Meur, Nolwenn with Gentleman, Robert (2008 September 12) “Modeling synthetic lethality”, in Genome Biology‎^[2], volume 9, →DOI, archived from the original on 14 October 2012, page R135